![]() ![]() In a normal population, it was estimated that two percent of people had PICA-VA on the right side. A review on vertebrobasilar ischemic strokes found that three of 39 patients (7.7%) had PICA-VA by pathological or angiographic examinations. PICA termination of VA (PICA-VA) is occasionally found on routine brain magnetic resonance angiography (MRA) however, only a few studies to date have reported the prevalence of this vascular variant. Anatomical variations of VA may be present as complete or partial duplication, asymmetry due to unilateral hypoplasia, or termination into its principal branch, the posterior inferior cerebellar artery (PICA). The vertebral arteries (VAs) are typically arising from the subclavian artery, ascending in the neck and uniting to form the single basilar artery (BA). However, the sample is small, and further studies are needed with larger sample size for confirmation. The higher prevalence of PICA-VA in the patient group with smaller diameter of VA, BA and PCA reflected its clinical significance, suggesting that PICA-VA may have a detrimental impact on cerebral hemodynamics. 1.6 ± 0.1 mm, p = 0.006) were also noted in the PICA-VA group. Moreover, a smaller diameter of the BA (3.2 ± 0.5 mm vs. In comparison with the non-PICA-terminating group, the PICA-VA has a smaller diameter (3.7 ± 0.7 mm vs. Most measurements (73.3%) of PICA-VA did not fit the criteria of VA hypoplasia. The prevalence of PICA-VA was higher in the patient group than in the controls (18.7% vs. ![]() We compared the prevalence of PICA-VA and associated hemodynamic parameters between the patients with and without PICA-VA, and investigated their relationships with VA hypoplasia. PICA termination of the VA (PICA-VA) was identified as the VA not communicating with the basilar artery (BA) but ending into a PICA. Eighty healthy subjects who had MRA check-up were recruited as controls. A total of 80 patients with clinically evident cerebrovascular events in posterior circulation were examined by duplex sonography and magnetic resonance angiography (MRA). We aimed to investigate the clinical significance of this cerebrovascular variant. A vertebral artery (VA) terminating in a posterior inferior cerebellar artery (PICA) is often considered to be a normal variation associated with VA hypoplasia. ![]()
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